Question 1

What stocks has ORBIMED ADVISORS LLC been buying?

Accepted Answer

InsiderAct tracks all open-market stock purchases disclosed by ORBIMED ADVISORS LLC via SEC Form 4 filings. These are publicly disclosed transactions that corporate insiders must file with the SEC within 2 business days of any stock transaction.

Question 2

How do I interpret an insider's transaction history?

Accepted Answer

Focus on open-market purchases (Form 4 code "P"), which represent voluntary personal capital commitments. Large purchases ($100,000+), repeated buying over time, and purchases during price declines are the most meaningful signals. Option exercises, stock awards, and automatic plan transactions are less informative.

Question 3

Are insider transactions reliable investment signals?

Accepted Answer

Insider buying is generally a more reliable signal than selling. Insiders buy for one primary reason — they believe the stock will rise. The strongest buying signals involve large dollar amounts, purchases during price declines, and cluster buying where multiple insiders buy simultaneously.

Question 4

Where can I see all of ORBIMED ADVISORS LLC's recent Form 4 filings?

Accepted Answer

All Form 4 filings by ORBIMED ADVISORS LLC are available on this InsiderAct profile page, sourced directly from SEC EDGAR. Each transaction shows the date, shares bought or sold, price per share, transaction code, and resulting ownership position. You can also view the original filing on SEC EDGAR for the complete disclosure.

Question 5

What is the difference between an officer and a director insider purchase?

Accepted Answer

Officer purchases (CEOs, CFOs, COOs) are generally considered stronger signals than director purchases because officers have deeper day-to-day visibility into company operations and financials. A director may be buying for governance or relationship reasons. Both are meaningful, but C-suite officer buying carries more informational weight — especially for large, discretionary purchases.


2026-06-02	2026-05-28	QTTB Q32 Bio Inc.	Director	Purchase	1,250,000	$8.00	$10,000,000
2026-06-02	2026-05-28	QTTB Q32 Bio Inc.	Director	Purchase	625,000	$8.00	$5,000,000
2026-05-30	2026-05-27	SION Sionna Therapeutics, Inc.	Director	Sale	101	$44.49	$4,493
2026-05-11	2026-05-11	SION Sionna Therapeutics, Inc.	Director	Sale	184,639	$46.22	$8,534,015
2026-05-11	2026-05-08	SION Sionna Therapeutics, Inc.	Director	Sale	59,767	$44.58	$2,664,413
2026-05-11	2026-05-07	SION Sionna Therapeutics, Inc.	Director	Sale	48,546	$44.61	$2,165,637
2026-04-23	2026-04-21	PRLD Prelude Therapeutics Inc	Director	Purchase	1,689,189	$4.44	$7,499,999
2026-04-23	2026-04-21	PRLD Prelude Therapeutics Inc	Director	Purchase	1,126,126	$4.44	$4,999,999
2026-04-22	2026-04-18	SION Sionna Therapeutics, Inc.	Director	Sale	2,948	$44.52	$131,245
2026-04-22	2026-04-17	SION Sionna Therapeutics, Inc.	Director	Sale	52,397	$44.68	$2,341,098

ORBIMED ADVISORS LLC

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